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Muscle Weakness Tied to Poor Mitochondria Function

Poorly working mitochondria — small energy-producing cell compartments — may drive muscle weakness or wasting in a new mouse model of porphyria, a study suggests. “In some cases, muscle atrophy [is] present in porphyria; however, the underlying mechanism is still unknown,” its authors wrote. These findings may therefore provide…

Insulin Resistance Common in AIP, Study Finds

Insulin resistance, a phenomenon in which cells in the body become unable to draw energy from blood sugar, appears to be more common in people with acute intermittent porphyria (AIP) than previously thought, according to a recent study. Investigators also noted that experiments performed in a mouse model indicated…