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May 25, 2022 News by Marta Figueiredo, PhD

Suppressing Liver Signaling Pathway May Help to Treat Porphyria

Suppressing Wnt/beta-catenin — a signaling pathway that plays a key role in liver health — significantly reduced liver damage and the porphyrin deposits whose accumulation cause porphyria in a mouse model of the disease, a study shows. Notably, these beneficial effects were associated with lower levels of enzymes involved in…

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