Two new algorithms that can accurately diagnose acute and cutaneous porphyria have been developed and validated, a study from Belgium reports. According to study’s authors, these algorithms can be used to help clinicians correctly interpret porphyria-related lab tests. “To our knowledge, this is the first time that diagnostic algorithms…
After the death of a 20-year-old man with erythropoietic protoporphyria (EPP), clinicians in Japan reported that a split liver transplant — a procedure in which an organ donor’s liver is divided and transplanted into two different people — may not be an effective treatment for EPP patients with liver…
In women with acute hepatic porphyria (AHP), increased levels of heme precursors during pregnancy were not accompanied by symptom worsening, and most patients had no AHP-related complications, a Swedish study reports. Nonetheless, given that “it can be challenging to differentiate between manifestations of an acute attack and obstetrical,…
Regular iron infusions given to treat anemia caused a woman with a rare mutation in the uroporphyrinogen decarboxylase (UROD) gene to develop porphyria cutanea tarda (PCT). Her case was described in the report, “Iatrogenic Iron Overload Causing Porphyria Cutanea Tarda in a Patient With a Rare Nonsense Heterozygous…
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